Tag: panella

December 12, 2020

Bioavailable wine pomace attenuates oxalate-induced type II epithelial mesenchymal transition and preserve the differentiated phenotype of renal MDCK cells

The useful renal epithelium consists of differentiated and polarized tubular cells with a powerful actin cortex and specialised cell-cell junctions. If, beneath pathological situations, these cells have to withstand increased kidney osmolarity, they should activate various mechanisms to outlive exterior nephrotoxic brokers equivalent to irritation and oxidative stress. Wine pomace polyphenols exert protecting results on renal cells. On this examine, two wine-pomace merchandise and their protecting results […]