Ethnopharmacological relevance: Species of the genus Vepris are utilized in conventional African pharmacopeia for the therapy of assorted situations, together with continual ailments and different parasitic. Additional makes use of are in opposition to whooping cough and colic in kids and as an antidote in opposition to snakebite. Knowledge introduced will allow the scientists to work on this genus making use of the so-called “ethnopharmacologic method”, which can lead in direction of the invention of the efficient, secure plant medicinal merchandise.
Goal of the assessment: This assessment article goals to collate and analyse the obtainable info on the normal makes use of, phytochemistry, pharmacology, and toxicological facets of Vepris species as a way to discover the developments and views for additional research.
Methodology: The current assessment paper collected the literature printed previous to August 2020 on the ethnomedicinal makes use of, phytochemistry, and pharmacology of the genus Vepris. The obtainable details about the genus Vepris was collected by way of Google Books, Google Scholar, PubMed, ScienceDirect, SciFinder, Net of Science, and different web sources. The World Biodiversity Data Facility (www.gbif.org), Vegetation of the world on-line (www.plantsoftheworldonline.org), and The Plant Record (www.theplantlist.org) databases had been used to confirm the scientific names and supply distribution info of Vepris species.
Outcomes: Complete evaluation of the literature offered info on ethnopharmacological makes use of of 30 species out of 83 members within the genus. A complete of 213 compounds – predominantly alkaloids – had been reported along with outcomes from antioxidant, cytotoxic, antimicrobial, antiplasmodial, antitrypanosomal, antileishmanial, antidiabetic, antipyretic, analgesic, insect antifeedant, and toxicity assays. Arborinine (49) and skimmianine (4) remoted from the leaves of V. trichocarpa had been examined poisonous in rat skeletal myoblast cell line L6, a secure skeletal muscle progenitor cell line, whereas the leaves of V. heterophylla, the stem bark of V. louisii, and the roots of V. uguenensis had been proven to be poisonous in opposition to mannequin organisms T. castaneum (Tenebrionidae), H. bakeri (Trychostrongylidae), and M. domestica (Muscidae), respectively. As well as, 6,7-methylenedioxy-5-hydroxy-8-methoxy-dictamnine (40) remoted from the leaves of a mixed pattern of V. renieri + V. suaveolens displayed an especially low IC50 of 0.67 μM in opposition to the conventional fibroblastic lung cell line MRC-5 indicating excessive toxicity. Thus, medical use of those plant elements, as properly of the stem bark of V. verdoorniana used domestically in poison fishing, needs to be averted if various therapies exist. Moreover, a superb variety of considerably in vitro bioactive compounds have been reported from the genus Vepris: in opposition to malaria and in opposition to microbial infections.
Conclusions: Numerous Vepris species had been discovered for use in conventional African pharmacopeia. Nevertheless, few of those species had been studied for his or her bioactive chemical constituents with even fewer bioassay-guided isolation research being reported. Furthermore, detailed pharmacological research in animal fashions to discover their mode of motion weren’t reported. Due to this fact, future research ought to deal with these facets. As well as, we wish to suggest additional analysis on some considerably bioactive crude extracts that had been recognized on this assessment: V. leandriana; V. lanceolata; V. nobilis; and V. trichocarpa, in addition to these vegetation reported for use in opposition to continual ailments.

Toxicological Threat Evaluation in Knowledge-Poor Nations: A Narrative Method to Feed an “Consciousness Elevating-Group Empowerment” Vortex

Background and aims: With globalization of tradition and merchandise, decisions and behaviors related to the unawareness of toxicological danger elements lead to human and environmental poisonous exposures together with well being disparities. Poisonous exposures are danger elements for malnutrition and ailments, impairing the possibilities of being wholesome and having a wholesome maturity for present and subsequent era(s). Rising analysis funds, infrastructures, analytical knowledge and danger evaluation is a actuality properly price consideration in sub-Saharan Africa.
These nations are nonetheless unprotected these days and are notably uncovered and data-poor in respect to danger elements (e.g., neurotoxicants, immunotoxicants and endocrine disruptors). This paper presents how-based on scientific literature-low-resource nations could obtain extra with much less. As one of many world’s most necessary rising markets, Africa can, and will, assess the advantages and dangers of modernity versus custom and ask for secure and high quality merchandise at inexpensive costs whereas producing secure and nutritious meals. Supplies and Strategies: Exempla and experiences of danger evaluation based mostly on participant commentary in area anthropological analysis, shopper safaris and reportages within the area of meals security, environmental well being and shopper merchandise are mentioned when it comes to “narrative prevention” and its energy to spotlight beforehand unrecognized/missed real-life danger situations. Information return initiatives are mentioned in gentle of their energy to feed consciousness elevating, knowledgeable alternative and empowerment of communities.
Outcomes: In some circumstances, knowledge exist however stay too sparse, unknown or underused; in different circumstances, the data is completely uncared for. When there may be worldwide scientific proof, a diagnostic danger evaluation is possible. Regardless of important useful resource constraints, correctly science-driven focused reportages in data-poor nations can bridge the gaps between worldwide scientific data and the implementation of related findings in an “awareness-empowerment vortex”. When a transparent message selling wholesome decisions and behaviors is given, African communities are prepared to reply.  Conclusions: Poor expertise are an avoidable consequence of low nationwide earnings. Narrative prevention doesn’t change scientific analysis however stimulates scientific analysis and toxicological danger evaluation through the ongoing danger transition in Africa.

96-Well Plate

1996-2
EUR 104

96 WELL PCR SEGMENTED PLATE

PCR-96-SG-C 10/pk
EUR 145
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

Pan-Ras Activation Assay

STA-400 20 assays
EUR 757
Description: Our Ras Activation Assays use visible agarose beads to selectively precipitate the active form of specific Ras protein of interest. The precipitated small GTPase is then detected by Western blot using a target-specific antibody included in the kit. Assays are available to detect specific isoforms H-Ras, K-Ras, and N-Ras, as well as a Pan-Ras assay that detects all three isoforms.

H-Ras Activation Assay

STA-400-H 20 assays
EUR 757
Description: Our Ras Activation Assays use visible agarose beads to selectively precipitate the active form of specific Ras protein of interest. The precipitated small GTPase is then detected by Western blot using a target-specific antibody included in the kit. Assays are available to detect specific isoforms H-Ras, K-Ras, and N-Ras, as well as a Pan-Ras assay that detects all three isoforms.

K-Ras Activation Assay

STA-400-K 20 assays
EUR 757
Description: Our Ras Activation Assays use visible agarose beads to selectively precipitate the active form of specific Ras protein of interest. The precipitated small GTPase is then detected by Western blot using a target-specific antibody included in the kit. Assays are available to detect specific isoforms H-Ras, K-Ras, and N-Ras, as well as a Pan-Ras assay that detects all three isoforms.

N-Ras Activation Assay

STA-400-N 20 assays
EUR 757
Description: Our Ras Activation Assays use visible agarose beads to selectively precipitate the active form of specific Ras protein of interest. The precipitated small GTPase is then detected by Western blot using a target-specific antibody included in the kit. Assays are available to detect specific isoforms H-Ras, K-Ras, and N-Ras, as well as a Pan-Ras assay that detects all three isoforms.

NATtrol Zika Virus Stock (Qualitative) (1 mL)

TEST 1 mL
EUR 1106.64
Description: Please contact Gentaur in order to receive the datasheet of the product.

96-Well Vacuum System

SD5011 1 UNIT
EUR 324.05

Solid 96 well plates

MC15F-BIO 10 plates(2X5 plates in a transparent bag)
EUR 179.31
Description: Solid 96 well plates BIOTIN COATED Color:Clear blocking:Standard

Solid 96 well plates

MC15F-BIO-W 10 plates(2X5 plates in a transparent bag)
EUR 236.01
Description: Solid 96 well plates BIOTIN COATED Color:Clear blocking:Non proteic

Solid 96 well plates

MCB15F-BIO 10 plates(2X5 plates in a transparent bag)
EUR 184.98
Description: Solid 96 well plates BIOTIN COATED Color:Black blocking:Standard

Solid 96 well plates

MCB15F-BIO-W 10 plates(2X5 plates in a transparent bag)
EUR 239.79
Description: Solid 96 well plates BIOTIN COATED Color:Black blocking:Non proteic

Solid 96 well plates

MCW15F-BIO 10 plates(2X5 plates in a transparent bag)
EUR 184.98
Description: Solid 96 well plates BIOTIN COATED Color:White blocking:Standard

Solid 96 well plates

MCW15F-BIO-W 10 plates(2X5 plates in a transparent bag)
EUR 239.79
Description: Solid 96 well plates BIOTIN COATED Color:White blocking:Non proteic

96-Well White Plates

M1354-2
EUR 131

96-Well Black Plates

M1355-2
EUR 131

PreS2-Ag ELISA test

96 96T/Box Ask for price
Description: ELISA based test for quantitative detection of PreS2-Ag

96 well filter plate (960ul each well)

SD5006 12UNIT
EUR 96.54

Polystyrene-bottomed 96-well plate (ELISA)

CT361 6
EUR 73

OxiSelect 96-Well Comet Assay Kit

STA-355 96 assays
EUR 427
Description: Our OxiSelect 96-Well Comet Assay Kits provide a higher-throughput way to screen for general DNA damage, regardless of the source or nature of the damage. Kits contain Comet Slides, reagents, and a fluorescent dye to visualize cells under an epifluorescence microscope.

OxiSelect 96-Well Comet Assay Kit

STA-355-5 5 x 96 assays
EUR 1633
Description: Our OxiSelect 96-Well Comet Assay Kits provide a higher-throughput way to screen for general DNA damage, regardless of the source or nature of the damage. Kits contain Comet Slides, reagents, and a fluorescent dye to visualize cells under an epifluorescence microscope.

96-Well ROCK Activity Assay Kit

STA-416 96 assays
EUR 856
Description: Rho-associated Kinase (ROCK) mediates Rho signaling and reorganizes the actin cytoskeleton by phosphorylation of several substrates that contribute to the assembly of actin filaments and contractility. ROCK inactivates myosin phosphatase through the specific phosphorylation of myosin phosphatase target subunit 1 (MYPT1) at Thr-696, which results in an increase in the phosphorylated content of the 20-kDa myosin light chain (MLC20). Our 96-Well ROCK Activity Assay Kit uses a safe, non-radioactive format to measure the level of active Rho Kinase in cell or tissue lysates. The kit contains a strip-well plate pre-coated with recombinant MYPT1.

96-Well ROCK Activity Assay Kit

STA-416-5 5 x 96 assays
EUR 3524
Description: Rho-associated Kinase (ROCK) mediates Rho signaling and reorganizes the actin cytoskeleton by phosphorylation of several substrates that contribute to the assembly of actin filaments and contractility. ROCK inactivates myosin phosphatase through the specific phosphorylation of myosin phosphatase target subunit 1 (MYPT1) at Thr-696, which results in an increase in the phosphorylated content of the 20-kDa myosin light chain (MLC20). Our 96-Well ROCK Activity Assay Kit uses a safe, non-radioactive format to measure the level of active Rho Kinase in cell or tissue lysates. The kit contains a strip-well plate pre-coated with recombinant MYPT1.

CometAssay 96 Well ES Starter Kit

4253-096-ESK 1 Kit
EUR 3124.4

96-well Viral DNA/RNA Kit

K1417-1
EUR 392

96-well Viral DNA/RNA Kit

K1417-4
EUR 1023

96 WELL CLEAR PCR PLATE FOR ABI

PCR-96-AB-C 10/pk
EUR 167
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

96 WELL CLEAR PCR MICROPLATE. PRE-STERILIZED

PCR-96-C-S 10/pk
EUR 183
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

96 WELL CLEAR, FLAT TOP PCR MICROPLATE

PCR-96-FLT-C 25/pk
EUR 202
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

96 WELL FULL SKIRT PCR MICROPLATES. CLEAR

PCR-96-FS-C 10/pk
EUR 145
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

96 WELL PCR MICROPLATES FOR MEGA BASE

PCR-96-MB-C 10/pk
EUR 145
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

96 WELL FLUORESCENT YELLOW PCR STORAGE RACK

R-96-PCR-FY 5/pk
EUR 119
Description: Micro Tubes; Racks Tubes - Axygen

1.2ML 96 WELL DEEP WELL PLATE HIGH CLARITY

P-DW-12-HC 5/pk
EUR 152
Description: Deep Well/Assay Plates - Axygen; Deep-well plates - Axygen

Adapter for 96 well plate

3510147 1unit
EUR 5581

96-Well Rack, Reversible, Blue

R577-B 1 UNIT
EUR 54.05

96-Well Rack, Reversible, Green

R577-G 1 UNIT
EUR 54.05

96-Well Rack, Reversible, Natural

R577-N 1 UNIT
EUR 54.05

96-Well Rack, Reversible, Pink

R577-P 1 UNIT
EUR 54.05

96-Well Rack, Reversible, Purple

R577-V 1 UNIT
EUR 54.05

96-Well Rack, Reversible, Yellow

R577-Y 1 UNIT
EUR 54.05

Black 96 Well Plate, 1EA

X025-1EA 1EA
EUR 73

Avidin CovaLinked 96-well Plates

6521-5
EUR 255

Streptavidin coated 96-well Plate

6523-5
EUR 327

96 Well Half-Area Microplates

M1356-2 2 Plates
EUR 146

Glucose colorimetric micro assay kit, 96 test, Quantitative

1380-GLC-1 1 kit
EUR 286

Cholesterol colorimetric micro assay kit, 96 test, Quantitative

1390-CHL-1 1 kit
EUR 529

Cholesterol Fluorometric micro assay kit, 96 test, Quantitative

1395-CHL-1 1 kit
EUR 347

Glycogen fluorometric micro assay kit, 96 test, Quantitative

1530-GLY-1 1 kit
EUR 529

Hemoglobin colorimetric micro assay kit, 96 test, Quantitative

1540-HEM-1 1 kit
EUR 286

Triglyceride colorimetric micro assay kit, 96 test, Quantitative

1550-TGL-1 1 kit
EUR 286

H-Ras Activation Assay Kit, Trial Size

STA-400-H-T 5 assays
EUR 403
Description: Our Ras Activation Assays use visible agarose beads to selectively precipitate the active form of specific Ras protein of interest. The precipitated small GTPase is then detected by Western blot using a target-specific antibody included in the kit. Assays are available to detect specific isoforms H-Ras, K-Ras, and N-Ras, as well as a Pan-Ras assay that detects all three isoforms.

K-Ras Activation Assay Kit, Trial Size

STA-400-K-T 5 assays
EUR 403
Description: Our Ras Activation Assays use visible agarose beads to selectively precipitate the active form of specific Ras protein of interest. The precipitated small GTPase is then detected by Western blot using a target-specific antibody included in the kit. Assays are available to detect specific isoforms H-Ras, K-Ras, and N-Ras, as well as a Pan-Ras assay that detects all three isoforms.

N-Ras Activation Assay Kit, Trial Size

STA-400-N-T 5 assays
EUR 403
Description: Our Ras Activation Assays use visible agarose beads to selectively precipitate the active form of specific Ras protein of interest. The precipitated small GTPase is then detected by Western blot using a target-specific antibody included in the kit. Assays are available to detect specific isoforms H-Ras, K-Ras, and N-Ras, as well as a Pan-Ras assay that detects all three isoforms.

Pan-Ras Activation Assay Kit, Trial Size

STA-400-T 5 assays
EUR 403
Description: Our Ras Activation Assays use visible agarose beads to selectively precipitate the active form of specific Ras protein of interest. The precipitated small GTPase is then detected by Western blot using a target-specific antibody included in the kit. Assays are available to detect specific isoforms H-Ras, K-Ras, and N-Ras, as well as a Pan-Ras assay that detects all three isoforms.

96-well GEL Purification Kit (1 prep)

FAGKE-96001 1 prep
EUR 158

96-well GEL Purification Kit (2 prep)

FAGKE-96002 2 preps
EUR 213

96-well GEL Purification Kit (4 prep)

FAGKE-96004 4 preps
EUR 317

96-well Total RNA Kit (1 plates)

FATRE-96001 1 prep
EUR 194

96-well Total RNA Kit (2 plates)

FATRE-96002 2 preps
EUR 281

96-well Total RNA Kit (4 plates)

FATRE-96004 4 preps
EUR 448

96-Well Plate PCR Products Purification Kit

BS365 5XPlates, 480prep
EUR 250.31

96-Well Plate PCR Products Purification Kit

BS3652 2xPlates, 192prep
EUR 155.16

96-Well Plate DNA Cleanup Miniprep Kit

BS369 5XPlates, 480prep
EUR 250.31

96-Well Plate DNA Cleanup Miniprep Kit

BS3692 2xPlates, 192prep
EUR 155.16

96-Well Plate Plasmid DNA Miniprep Kit

BS415 5XPlates, 480prep
EUR 250.31

96-Well Plate Plasmid DNA Miniprep Kit

BS4152 2XPlates, 192prep
EUR 155.16

CytoSelect 96-well Leukocyte-endothelium Adhesion Kit

CBA-210 100 assays
EUR 577
Description: Leukocyte or tumor cell interactions with vascular endothelium consist of a cascade of processes including the firm attachment of cells to endothelial cell adhesion molecules. The CytoSelect Endothelium Adhesion Assays provide a robust system for the quantitative determination of interactions between leukocytes or tumor cells and endothelium. Adherent cells can be easily quantified on a fluorescence plate reader.

CytoSelect 96-well Leukocyte-epithelium Adhesion Kit

CBA-211 100 assays
EUR 577
Description: Leukocyte or tumor cell interactions with vascular endothelium consist of a cascade of processes including the firm attachment of cells to endothelial cell adhesion molecules. The CytoSelect Leukocyte Epithelium Adhesion Assay provides a robust system for the quantitative determination of interactions between leukocytes and epithelium. Adherent cells can be easily quantified on a fluorescence plate reader.

96-well Checkpoint Kinase Activity Assay Kit

STA-414 96 assays
EUR 757
Description: Our 96-well Checkpoint Kinase Activity Assay Kit provides a non-isotopic, sensitive and specific method to monitor checkpoint kinase activity using its physiological substrate; it can also be used in screening checkpoint kinase inhibitors.

96-well Checkpoint Kinase Activity Assay Kit

STA-414-5 5 x 96 assays
EUR 3060
Description: Our 96-well Checkpoint Kinase Activity Assay Kit provides a non-isotopic, sensitive and specific method to monitor checkpoint kinase activity using its physiological substrate; it can also be used in screening checkpoint kinase inhibitors.

96-Well Plate Viral DNA Miniprep Kit

VT92032 2XPlates, 192prep
EUR 413.22

96 well DNA plate with membrane (960ul each well)

SD5007 12UNIT
EUR 242.7

96 well RNA plate with membrane (960ul each well)

SD5009 12UNIT
EUR 260.97

96 well plates - 12x8 Well Strips on 12x8 frame

MT0STF2-SA5-200 10 plates(2X5 plates in a transparent bag)
EUR 219
Description: 96 well plates - 12x8 Well Strips on 12x8 frame STREPTAVIDIN COATED Color:Clear blocking:Standard

96 well plates - 12x8 Well Strips on 12x8 frame

MT15F2-BIO 10 plates(2X5 plates in a transparent bag)
EUR 181.2
Description: 96 well plates - 12x8 Well Strips on 12x8 frame BIOTIN COATED Color:Clear blocking:Standard

96 well plates - 12x8 Well Strips on 12x8 frame

MT15F2-BIO-W 10 plates(2X5 plates in a transparent bag)
EUR 237.9
Description: 96 well plates - 12x8 Well Strips on 12x8 frame BIOTIN COATED Color:Clear blocking:Non proteic

96 well plates - 12x8 Well Strips on 12x8 frame

MTB15F2-BIO 10 plates(2X5 plates in a transparent bag)
EUR 183.09
Description: 96 well plates - 12x8 Well Strips on 12x8 frame BIOTIN COATED Color:Black blocking:Standard

96 well plates - 12x8 Well Strips on 12x8 frame

MTB15F2-BIO-W 10 plates(2X5 plates in a transparent bag)
EUR 239.79
Description: 96 well plates - 12x8 Well Strips on 12x8 frame BIOTIN COATED Color:Black blocking:Non proteic

96 well plates - 12x8 Well Strips on 12x8 frame

MTW0STF2-SA5-200 10 plates(2X5 plates in a transparent bag)
EUR 220.89
Description: 96 well plates - 12x8 Well Strips on 12x8 frame STREPTAVIDIN COATED Color:White blocking:Standard

96 well plates - 12x8 Well Strips on 12x8 frame

MTW15F2-BIO 10 plates(2X5 plates in a transparent bag)
EUR 183.09
Description: 96 well plates - 12x8 Well Strips on 12x8 frame BIOTIN COATED Color:White blocking:Standard

96 well plates - 12x8 Well Strips on 12x8 frame

MTW15F2-BIO-W 10 plates(2X5 plates in a transparent bag)
EUR 239.79
Description: 96 well plates - 12x8 Well Strips on 12x8 frame BIOTIN COATED Color:White blocking:Non proteic

96 WELL CLEAR PCR HALF SKIRT AMPLIFICATION PLATE

PCR-96-HS-C 10/pk
EUR 159
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

96 WELL SITTING DROP HIGH THROUGHPUT CRYSTALLOGRAPHY PLATE.

CP-AXYGEM-96-50 10/pk
EUR 457
Description: Crystallography Plates; Crystallography Plates - Axygen

96 well plates - 12x8 Well Breakable Strips on single well holding frame

MG0STF-SA5-200 10 plates(2X5 plates in a transparent bag)
EUR 219
Description: 96 well plates - 12x8 Well Breakable Strips on single well holding frame STREPTAVIDIN COATED Color:Clear blocking:Standard

96 well plates - 12x8 Well Breakable Strips on single well holding frame

MG0STF-SA5-200-W 10 plates(2X5 plates in a transparent bag)
EUR 247.35
Description: 96 well plates - 12x8 Well Breakable Strips on single well holding frame STREPTAVIDIN COATED Color:Clear blocking:Non proteic

96 well plates - 12x8 Well Breakable Strips on single well holding frame

MG15F-BIO 10 plates(2X5 plates in a transparent bag)
EUR 181.2
Description: 96 well plates - 12x8 Well Breakable Strips on single well holding frame BIOTIN COATED Color:Clear blocking:Standard

96 well plates - 12x8 Well Breakable Strips on single well holding frame

MG15F-BIO-W 10 plates(2X5 plates in a transparent bag)
EUR 237.9
Description: 96 well plates - 12x8 Well Breakable Strips on single well holding frame BIOTIN COATED Color:Clear blocking:Non proteic

96 well plates - 12x8 Well Breakable Strips on single well holding frame

MGB0STF2-SA5-200 10 plates(2X5 plates in a transparent bag)
EUR 220.89
Description: 96 well plates - 12x8 Well Breakable Strips on single well holding frame STREPTAVIDIN COATED Color:Black blocking:Standard

96 well plates - 12x8 Well Breakable Strips on single well holding frame

MGB0STF2-SA5-200-W 10 plates(2X5 plates in a transparent bag)
EUR 249.24
Description: 96 well plates - 12x8 Well Breakable Strips on single well holding frame STREPTAVIDIN COATED Color:Black blocking:Non proteic

96 well plates - 12x8 Well Breakable Strips on single well holding frame

MGB15F2-BIO 10 plates(2X5 plates in a transparent bag)
EUR 183.09
Description: 96 well plates - 12x8 Well Breakable Strips on single well holding frame BIOTIN COATED Color:Black blocking:Standard

96 well plates - 12x8 Well Breakable Strips on single well holding frame

MGB15F2-BIO-W 10 plates(2X5 plates in a transparent bag)
EUR 239.79
Description: 96 well plates - 12x8 Well Breakable Strips on single well holding frame BIOTIN COATED Color:Black blocking:Non proteic

96 well plates - 12x8 Well Breakable Strips on single well holding frame

MGW0STF-SA5-200 10 plates(2X5 plates in a transparent bag)
EUR 220.89
Description: 96 well plates - 12x8 Well Breakable Strips on single well holding frame STREPTAVIDIN COATED Color:White blocking:Standard
Whereas African populations more and more aspire to enhance life expectancy in well being, rising publicity to such new well being danger elements in sub-Saharan Africa wants top-down decisions for ailments prevention, One Well being, in addition to public consciousness and empowerment in direction of on a regular basis habits and well being protecting decisions.